The core activity of Humabs BioMed SA is the discovery and development of anti-infective immunotherapies for the treatment of viral and bacterial diseases, including those caused by Zika, Ebola, Rabies, Dengue and other Flaviviruses. The company focuses on the development of therapeutics up to clinical proof of concept and has a broad pipeline of development candidates.
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Development of Immunotherapies
Development of antibody- and T-cell engager–based therapeutics for infectious diseases, cancer and other serious conditions with high unmet medical need.
Antibody and T-cell Engager Development Platform
Platform for the identification, optimisation and further development of antibodies, antibody fragments and T-cell engagers using proprietary discovery methods and AI-supported protein engineering tools.
PRO-XTEN® Masking Platform
Protease-cleavable masking platform for targeted activation of therapeutics in the tumour microenvironment, focusing on T-cell engagers and other applications in oncology and infectious diseases.
Treatment of chronic hepatitis delta
Development of a chronically suppressive therapy with tobevibart and elebsiran; ongoing Phase 3 programme for the treatment of chronic hepatitis delta.
Oncology Therapies
Development of PRO-XTEN®-masked T-cell engagers against HER2, EGFR and PSMA, as well as other undisclosed targets for solid tumours.