PROTEIN METRICS AG develops vendor-neutral mass spectrometry software for identification, characterization and quantitation of proteins and oligonucleotides across the biotherapeutic development process. Its product portfolio includes desktop and enterprise solutions such as Byos, Byonic and Byosphere for automated workflows, data analysis and reporting.
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Biotherapeutic protein characterization and analysis
Byos desktop software for comprehensive mass spectrometry workflows for characterizing biotherapeutic proteins, including automated analysis, inspection and reporting.
Peptide and protein identification
Byonic MS/MS search engine for comprehensive peptide and protein identification with modification search, glycopeptide search, wildcard search and reporting for high-throughput workflows.
Cloud enterprise platform for biotherapeutic mass spectrometry data
Byosphere cloud platform for management, analysis, reporting and collaboration with Deep Query, Dashboards, GxP-compliant data management and integrations with ELN/LIMS.
Intact mass analysis
Automated workflows for intact, sub-unit and native analysis with MS/MS annotation, deconvolution, glycopeptide characterization and reporting for biotherapeutic samples.
Peptide-level analysis
Workflows for protein- and peptide-related analyses with peptide identification, label-free quantification, PTM analysis, Peptide Manager and reporting.
Oligonucleotide analysis
High-throughput workflows for characterizing oligonucleotides with molecular weight determination, sequence confirmation, impurity profiling, digestion workflows and reporting.
Chromatogram analysis
Workflows for peak annotation, reference and comparison projects, peak integration, retention time matching, glycan analysis and reporting for chromatographic data.
De novo sequencing of monoclonal antibodies
Automated sequencing of unknown antibodies from LC-MS/MS data with enzymatic digestion, assembly of peptide sequences and confidence metrics.
Reconstruction of intact and charge variants
Workflows for reconstructing theoretical intact masses from peptide mapping data, comparison with experimental spectra and analysis of modifications and ADCs.
Higher-order structure analysis
HDX-MS workflows for analyzing protein dynamics and interactions with deuterium uptake calculation, visualization, reporting and structural views.
Multi-protein quantification
Workflows for complex protein mixtures with label-free quantification, proteome profiling, HCP quantification, MS quality checks and dashboards.
Dashboards and Deep Query
Real-time dashboards for automatic import, processing and display of mass spectrometry data and metadata with filtering, monitoring and project comparison.
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