The core activity of B'SYS GmbH is to provide services as a Contract Research Organization (CRO) in the field of Ion Channel Discovery for pharmaceutical companies. In particular, the company offers rapid screening services for new substances on ion channel drug targets, including safety services, discovery services, serum shift assays, action potential assays, ion channel trafficking assays, cardiac panel and cardiovascular toxicity tests.
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Products & services
Industry:Research & DevelopmentPharmaceutical Industry
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Ion channel screening with patch-clamp technology, automated and manual setups, fluorescence screening, and tests on ligand- and voltage-dependent ion channels.
Cell line generation
Stable cell line generation for ion channel targets, including cell line design, validated cell lines, and the CiPA cell line set for research applications.
Safety services
Tests to identify drug interactions with cardiac ion channels and QT prolongation, complemented by central nervous system safety checks.
Discovery services
Ion channel subtype selectivity screens and state-dependency analyses for sodium and calcium channels for lead identification and candidate selection.
GLP testing
GLP-compliant measurements under physiological conditions, including concentration verification of the dose solutions and standardized study procedures.
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