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DirectoryIndustryPharmaceutical IndustryBaselCabaletta Bio GmbH
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Cabaletta Bio GmbH

Summary

About the company

Cabaletta Bio GmbH is a clinical‑stage biotechnology company developing engineered T cell therapies for autoimmune diseases. It applies the Cabaletta Approach to B cell Ablation (CABA®) platform and is advancing rese‑cel, a fully human CD19‑CAR T candidate, in RESET™ Phase 1/2 trials to evaluate transient B‑cell depletion as a means to reset the immune system in conditions such as systemic lupus erythematosus, myositis, systemic sclerosis, generalized myasthenia gravis and pemphigus vulgaris.

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Industry:Pharmaceutical Industry
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Development of T-cell therapies for autoimmune diseases
Development of engineered T cell therapies and Chimeric Antigen Receptor T cells for Autoimmunity (CARTA) for the treatment of autoimmune diseases with B-cell involvement.
Rese-cel
Investigational fully human CD19 CAR T cell therapy with a 4-1BB co-stimulation domain, as a single-dose infusion for systemic lupus, myositis, systemic sclerosis, gMG and pemphigus vulgaris in clinical development.
Clinical Phase 1/2 trials within the RESET programme
Phase 1/2 clinical trials in lupus, myositis, systemic sclerosis, generalized myasthenia gravis and pemphigus vulgaris, including RESET-SLE, RESET-Myositis, RESET-SSc, RESET-MG and RESET-PV.
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Location

Hochbergerstrasse 70
4057 Basel

At a glance

Legal form
Limited Liability Company
UID
CHE-180.349.852
Founded
2024 · 2 years
Last commercial register change
October 1, 2025
Employees
21 to 50

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