The core activity of CovalX AG is the development and provision of technologies and services for the analysis of proteins and protein interactions, particularly through mass spectrometry. The focus is on the characterization of therapeutic proteins and providing solutions for the pharmaceutical industry and academic laboratories.
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Offering
Products & services
Industry:Medical Technology Industry
✓ Offered9
Epitope Mapping Service (HDX-MS/XL-MS)
Epitope mapping for antibodies and protein-protein interactions using HDX-MS and XL-MS, including sample QC with High-Mass MALDI MS plus peptide maps, contact maps and an analytical report.
De Novo Sequencing
Reference-free protein and antibody sequencing by MS/MS with multi-enzyme digestion, nano-LC-MS/MS, PTM and glycan profiling, plus QC with High-Mass MALDI MS.
mAb Characterization
Comprehensive antibody characterization with high-resolution LC-MS, intact MALDI-MS, PMF sequence verification, PTM, disulfide, glycan, aggregation and interaction analyses.
Protein Interaction Analysis
Analysis of intact protein complexes with High-Mass MALDI MS and chemical cross-linking to determine complex stoichiometry, binding partners and non-covalent interactions.
Immunoprecipitation Mass Spectrometry (IP-MS)
IP-MS for target identification, mechanism-of-action studies and biomarker discovery, with antibody pulldown, nano-LC-MS/MS, protein interaction lists and an analytical report.
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