Granite Bio AG is a biotechnology company developing first-in-class therapeutic antibodies for inflammatory, autoimmune and fibrotic diseases. Its pipeline includes GRT-001, an antibody that depletes pro-inflammatory monocytes and is in Phase 1b for inflammatory bowel disease, and GRT-002, an interleukin-3–blocking antibody in preclinical development expected to enter clinical trials in 2026.
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Development of first-in-class antibodies against inflammation, autoimmunity and fibrosis; pipeline with GRT-001 and GRT-002 for selective immunomodulation and new therapeutic approaches.
Development of therapies for inflammation, autoimmunity and fibrosis
Development of agents against inflammatory, autoimmune and fibrotic diseases; focus on key disease mechanisms, immunomodulation and selective depletion of pathogenic cells.
GRT-001
Therapeutic antibody for the depletion of pro-inflammatory monocytes; Phase 1a completed, currently Phase 1b in inflammatory bowel disease.
GRT-002
Therapeutic antibody against interleukin-3; developed preclinically for autoimmune inflammation, type II inflammation, itch and allergy.