The core activity of HARTIS Pharma consists of researching and developing therapeutics based on the potential benefits of High-Density-Lipoprotein (HDL), particularly through the regulation of membrane cholesterol and its liposoluble cargo activity of antioxidants. The company focuses on developing treatments for medical needs that have not been adequately addressed or cannot be treated sufficiently.
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Development of therapeutics for sickle cell disease
Development of oral and injectable active ingredients for the treatment of sickle cell disease, including HRT-001 for chronic SCD and HRT-002 for vaso-occlusive crises.
Development of HDL-based therapies
Revisiting the therapeutic potential of HDL to regulate cholesterol in the red blood cell membrane as well as to reduce oxidation and hemoglobin polymerisation.
Development of therapies for sickle cell trait and related pathologies
Investigation of potential therapeutic approaches for sickle cell trait as well as applications in thalassaemia, microcirculation and type 2 diabetes.
Development of antioxidant and lipophilic vitamin transport therapies
Transport of liposoluble vitamins and antioxidants with possible applications in skin conditions, age-related macular degeneration, Alzheimer and neurodegenerative diseases.
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